Cell Lines and Cell Cultures

Live human- and animal-derived cells and cell cultures suitable for a wide variety of cell culture-related experiments and procedures.

946 – 960 of 11,204 results

946

Eurofins Discoverx PathHunter CHO-K1 CXCR7 (CMKOR1) β-Arrestin Cell Line, 2 vials. (93-0248C2)

The PathHunter CXCR7 (CMKOR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL12/SDF-1α) based activation of CXCR7 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR7 and EA-tagged β-Arrestin-2. Activation of CXCR7 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.

Pricing & Availability

947

Eurofins Discoverx PathHunter CHO-K1 GCGR β-Arrestin Cell Line, 2 vials. (93-0241C2)

The PathHunter GCGR cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. glucagon) based activation of GCGR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GCGR and EA-tagged β-Arrestin-2. Activation of GCGR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.

Pricing & Availability

948

Eurofins Discoverx PathHunter CHO-K1 CCR1 β-Arrestin Cell Line, 2 vials. (93-0254C2)

The PathHunter CCR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL3) based activation of CCR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCR1 and EA-tagged β-Arrestin-2. Activation of CCR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.

Pricing & Availability

949

Eurofins Discoverx PathHunter U2OS GHSR1a β-Arrestin-1 Cell Line, 2 vials. (93-0242C3)

The PathHunter GHSR1a (ARR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ghrelin) based activation of GHSR1a GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GHSR1a and EA-tagged β-Arrestin-1. Activation of GHSR1a stimulates the recruitment of β-Arrestin-1 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.